Wibe Wagemans – the dynamic leader and serial entrepreneur – embarked on a journey when dozens before him had failed. Wibe laid the foundation of a biotech brand, Pardigm Inc., that changed home testing as we know it today. His AI breakthrough allows you to use your smartphone as a future standard for at-home diagnostic testing. Backed by two Stanford professors, this incredible venture not only cuts out all the middlemen and additional hardware readers but also removes the lab – a world first.
The first step was to get cortisol results on the spot, in minutes. A cortisol baseline has been eluding doctors forever. You might think cortisol only covers instant stress but that’s only 3% of its impact on the mind and body. So why should you care that 70% of the adult US population has imbalanced cortisol levels?
Experts call cortisol– for which there’s no proxy–the best window into our brain. Cortisol is behind all the top health issues: cardiovascular disease, aging & telomere shortening, obesity, diabetes, brain & mental health, infertility, menopausal symptoms, autoimmune diseases, athletic recovery, and Long Covid. Wibe and Dr. Bina Ph.D. wrote the book “Cortisol: The Master Hormone” which turned into an instant bestseller in 6 health and wellness categories. It’s the first systematic review of all published scientific literature on the relationship between Cortisol and various health conditions.
Causality was demonstrated in dozens more health issues than top scientists realized and they anticipate that more rigorous studies in humans will show similar causal effects previously demonstrated in mammals. Moreover, most cortisol effects are reversible with the proper regimens.
Pardigm developed a patented technology platform that can quantify, with lab scanner accuracy, 100’s biomarkers – neurodegenerative, cancer, cardiovascular, psychiatric and more, influencing the future of research and pharma, and creating TRULY personalized medicine.
Located in California, Pardigm provides faster access to care and health equity while lowering costs, eliminating logistics, and shortening turnaround times for diagnosis and treatment. By automating this incredibly labor-intensive process, they eliminate the need for labs in places where they don’t exist by making the collection of biomarkers easier and less expensive. And perhaps most crucially, they are combatting some of the biggest epidemics of the twenty-first century, including stress, obesity, cardiovascular disease, and mental health, while also improving patient outcomes and preventing disease.
The Man Behind the Idea – Wibe Wagemans
Wibe Wagemans, Founder & CEO of Pardigm, is a serial entrepreneur, and pioneer in mobile and AI technology. He was the first person in the world to create an AI bot and an online game on mobile. “Huuge Games,” his most recent business, went public in 2021 for $1.2 billion. He oversaw a $1 billion business at Nokia, and for the past 15 years, he has led companies in Silicon Valley.
Wibe Wagemans spent two years researching thousands of scientific papers on cortisol and other hormones and interviewing the world’s top scientists who have studied cortisol across many medical disciplines- endocrinology, gynecology, psychology, psychiatry, gastroenterology, physiology. He has a comprehensive understanding of the role cortisol plays in the human body, is an engaging speaker and can converse in ways that nonscientists can understand.
Since 2006, he’s been running and advising startups in Silicon Valley, where he built brands such as Angry Birds and Big Fish.
His work at Angry Birds, Big Fish, Huuuge Games Inc., and others earned him the Cannes Golden Lion award, the world record of No. 1 hits in the App Store, and several exits in excess of $500 million. His expertise in mobile technology and artificial intelligence provided the foundation for eventually resolving a major healthcare issue.
“I want to be remembered as a person who affects the lives of millions.” Professor Van Rossum, who is well known for her research on stress and obesity, said “When new technologies are created, cortisol home testing will become as commonplace as COVID tests [in 2021]. “Wibe Wagemans added, “We are working to make this happen.”
The Inception of Pardigm
Why should you care that cortisol and countless other biomarkers are nearly impossible to test at home? The top 5 health disorders are all caused by the master hormone, Cortisol. It is tied to stress. obesity, diabetes, problems with the mind, stress, as well as heart disease. 80% of adults have imbalances, making it one of the most prolific global health issues, but the effects are REVERSIBLE with proper management.
The science is crystal clear: Cortisol is the No. 1 or 2 cause of hundreds of health issues. The main problem is that cortisol requires highly specialized medical professionals to implement and interpret, which is not covered by medical insurance. It also needs laboratory processing and interpretation, creating a time lag that precludes real-time remedial action.
In the year 2021, Pardigm was conceptualized to develop a simple saliva test that monitors your cortisol rhythm in real-time, at home, on your mobile phone, along with a detailed program to help you optimize your cortisol levels. It enables you to take command of your health and control your master hormone.
The Key Differentiating Factors of Pardigm
- This is the first time any company has solved the point-of-care diagnostic problem for hundreds of quantitative biomarkers without the use of an external device/additional hardware.
- Pardigm developed a radically new way to quantify and help manage cortisol — at home, in real-time, using only your mobile phone.
- For the first time, everyone can now experience an accurate snapshot of their cortisol health – a picture of what’s happening inside their body and mind.
- Stress management is a huge trend and it’s being incorporated into fitness trackers by measuring HRV, and other products using sweat, hair samples or just psychological interventions. Consumers need to know that there is no scientific evidence supporting those measures. There is no proxy for cortisol.
- Cortisol testing and management can contribute to the alleviation of some of the most urgent global health issues and influence favorable outcomes for all.
Their vision is to fundamentally transform the diagnostic testing industry and tackle the top global health conditions in a radically new way!
In 2023, Pardigm aims to be on the market with cortisol testing and regimens, followed by vitamin D, thyroid, testosterone, estrogen, and hundreds of analytes in the future. The solution will unlock massive value and efficiency from an antiquated, 180-billion-dollar diagnostics industry because it brings the lab literally into your pocket. Within a few years, the startup idea is expected to flourish rapidly and impact millions of individuals.
Words of Wisdom
Combine an open mind with grit and magic happens.
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